Re: Higgenbotham's Dark Age Hovel
Posted: Sat Jun 08, 2024 2:04 am
"We can sort you out. No problem. We can help you," the doctor told Jennifer Hannington. Then he turned to her husband, Ciaran, and said: "But there's not much we can do for you."
The couple, who live in Yorkshire, England, had been trying for a baby for two years. They knew it could be difficult for them to conceive as Jennifer has polycystic ovarian syndrome, a condition that can affect fertility. What they had not expected was that there were problems on Ciaran's side, too. Tests revealed issues including a low sperm count and low motility (movement) of sperm. Worse, these issues were thought to be harder to treat than Jennifer's – perhaps even impossible.
https://www.bbc.com/future/article/2023 ... ity-crisis"In general, when you get below 40 million sperm per millilitre of semen, you start to see fertility problems," says Hagai Levine, professor of epidemiology at the Hebrew University of Jerusalem.
Sperm count, explains Levine, is closely linked to fertility chances. While a higher sperm count does not necessarily mean a higher probability of conception, below the 40 million/ml threshold the probability of conception drops off rapidly.
In 2022, Levine and his collaborators published a review of global trends in sperm count. It showed that sperm counts fell on average by 1.2% per year between 1973 to 2018, from 104 to 49 million/ml. From the year 2000, this rate of decline accelerated to more than 2.6% per year.
We are facing a public health crisis and we don't know if it's reversible – Hagai Levine
Levine argues this acceleration could be down to epigenetic changes, meaning, alterations to the way genes work, caused by environmental or lifestyle factors. A separate review also suggests epigenetics may play a part in changes in sperm, and male infertility.
"There are signs that it could be cumulative across generations," he says.
The idea that epigenetic changes can be inherited across generations has not been without controversy, but there is evidence suggesting it may be possible.
"This [declining sperm count] is a marker of poor health of men, maybe even of mankind," says Levine. "We are facing a public health crisis – and we don't know if it's reversible."
We are seeing the leading edge of this.Higgenbotham wrote: Fri Feb 23, 2024 9:54 pm First generation: (born around 1960 plus or minus a few years) Parents were not exposed to synthetic chemicals until they were adults. Anecdotally there seem to be a few more obese kids, geeky kids, gay kids, kids with allergies, kids needing orthodontics, etc., but nothing too alarming and kids seem to grow out of some of these problems. The birth rate for this generation falls a bit when adulthood is reached but nothing too dramatic. There may be a few years decrease in life expectancy becoming evident.
Second generation: (born around 1985 plus or minus a few years) First transgenerational effects may be seen, in other words, parents who were exposed to these things during their own fetal and childhood development start to have kids. In addition to what plagues the first generation born around 1960, hyperactivity, attention deficit disorder, autism, more severe allergies, diabetes, and other disorders become more common and less curable. Some are now common enough to have names and to be screened for. This generation sees a dramatic fall in their birthrate upon reaching adulthood.
Third generation: (born around 2015 plus or minus a few more years) Now going out on a limb. Transgenerational effects are now quite noticeable and influence the culture and economy to a great extent. There are lots more lesbian, gay, bisexual, and transgender adults compared to generations born before World War II, so many in fact that an acronym to describe this phenomenon is thought to be needed, LGBT. It is rare for a child not to have some kind of disorder. Disorders become even more severe; for example whereas many children born in 1960 may have been a bit geeky, now many are severely autistic. The birth rate for this generation takes a dramatic fall to less than half of the birthrate of the generation born before World War II.
Fourth generation: (born around 2045 plus or minus a few more years) Now really going out on a limb. Transgenerational effects in the mainstream American culture are now so severe that fertility and lifespan are affected to the point that it is evident mainstream culture is no longer viable. In most cases, disorders are so severe as to be irreversible and in many cases untreatable.
However, I believe it will be shown to be reversible in most cases if someone is willing to abandon the requirements of mainstream American culture.Male infertility contributes to approximately half of all cases of infertility and affects 7% of the male population.